SARTORIUS ARIUM MINI ULTRAPURE WATER SYSTEM

General Specifications Water purification method Adsorption by means of spherical activated carbon, catalyst, reverse osmosis, ion exchange, optional UV irradiation, and end-position particle |sterile filtration Dimensions: width×height×depth 280 × 509.4 × 530.7 mm Empty weight Approx. 13 kg Operating weight Approx. 23 kg Power supply 100–240 VAC; 50and60 Hz, 2 A (max.) Operating temperature 2°C–35°C at max. 80% relative humidity Storage temperature 5°C–45°C at max. 80% relative humidity Technical Specifications arium® mini plus flow diagram Pretreatment cartridge Product water outlet Conductivity Bag measurement arium® mini flow diagram Inlet (feed water) Product water outlet Bag UV lamp (185|254 nm) optional Conductivity measurement Ultrapure water cartridge Outlet (reject water) Final filter Inlet (feed water) Outlet (reject water) Pump Pump Pump Pump UV lamp (185|254 nm) optional Conductivity measurement Ultrapure water cartridge Final filter Ordering Information arium ® mini plus for the production of ASTM Type 1 ultrapure water and Type 3 pure water Scope of supply: 1 arium® mini plus, optional with UV lamp Order no. without UV lamp Order no. incl. UV lamp Description H2O-MA-T H2O-MA-UV-T arium ® mini plus,bench top device, flow capacity Type 3 pure water 8 l/h arium® mini plus Product Water Specifications Water type ASTM Type 1 ultrapure water Type 3 pure water Production output1 – Up to 8 l/h Water dispensing flow rate2 Up to 1.0 l/min Depressurized via ball valve Volume-controlled dispensing2 50 ml steps, between 0.05 and 5 l – Volume accuracy3 ± 3 % between 0.25 and 5 l – Typical conductivity 0.055 μS/cm compensated to 25 °C 6 < 20 µS/cm7 Typical resistivity 18.2 MO × cm compensated to 25 °C6 < 0.05 MO×cm7 TOC content4 (system with UV lamp) < 5 ppb – Microorganism content5 < 1 CFU/1,000 ml < 1 CFU/1,000 ml Particle content > 0.2 µm5 < 1/ml < 1/ml Typical ion retention – Up to 98% Retention of dissolved organic substances (MW > 300 Dalton) – > 99 % Particle and microorganism retention – > 99 % arium® mini plus Feed Water Specifications Exclusively potable tap water pursuant to the drinking water standards of the USA, the European Union, or Japan. Input pressure 0.5 – 6 bar, recommended > 2 bar Temperature 2–30°C Specific conductivity < 1500 µS/cm compensated to 25°C TOC < 2,000 ppb Max. total hardness (max. CaCO3) 360 ppm Free chlorine < 4 ppm Iron (total Fe content) < 0.1 ppm Fouling Index (SDI) < 10 Turbidity 0.2 µm4 < 1/ml arium® mini Feed Water Specifications Treated water via reverse osmosis, distillation or deionization. Input pressure Depressurized Temperature 2–30°C Specific conductivity < 100 µS/cm compensated to 25°C TOC < 50 ppb Turbidity < 1 NTU pH value 4–10 Ordering Information arium® mini, for the production of ASTM Type 1 ultrapure water Scope of supply: 1 arium® mini, optional with UV lamp Order no. without UV lamp Order no. incl. UV lamp Description H2O-MM-T H2O-MM-UV-T arium® mini bench top device, for manual feeding with pretreated feed water 1 Depending on the hydrostatic pressure, and connected accessories and|or final filter 2 Under constant operating conditions 3 When using an arium® sterile filter (Sartopore® 2 150) 4 Measured value output adjustable to 25 °C compensated or uncompensated – Excellent service lifetime and flow rates – Integrity tested – Validated according to HIMA and ASTM F-838-05 – Meets WFI quality standards pursuant to USP incl. USP plastic class VI test arium® Sterile Filter Sterile and particle-free water dispensing Technical Specifications | Ordering Information Description The arium® sterile filter (Sartopore® 2 150) is a sterile, ready-touse membrane filter capsule suitable for the most stringent requirements. Sartopore® 2 150 membrane filter capsules contain a hydrophilic, heterogeneous polyethersulfone double membrane. These provide excellent holding times and flow rates. The capsule is attached in the end position by means of a quick connector and reliably removes all particles > 0.2 µm and microorganisms in the last purification step. A hydrophobic PTFE membrane at the farthest point “upstream” allows for easy and clean ventilation of the capsule. Materials Membranes Asym. Polyethersulfone Bell assembly Polycarbonate Other plastics Polypropylene Pore size 0.45 µm + 0.2 µm Filtration area 0.015 m2 Inlet and outlet 4” plug-in connector Sterilization (max. 3 cycles) Autoclavable at 134°C, 1 bar, 30 min. Max. diffusion 1 ml/min @ 2.5 bar Min. bubble point 3.2 bar Order Number Description 5441307H4–CE–B arium® sterile filter (Sartopore® 2 150 Capsule), 0.2 µm pore size: (5 pcs) Intended Use On remote dispenser and display dispense units for device type: arium® mini and arium® mini plus arium® comfort I and comfort II arium® pro, pro DI, pro UF, pro UV and pro VF arium® 611 arium® remote dispensers – Production in accordance with DIN ISO 9001 – Easy to install – Certified quality All pleated Sartopore® 2 150 membrane filter units are validated as sterile filters for biopharmaceutical application according to the HIMA and ASTM F-838-05 guidelines (documentation available). During the manufacturing process, every capsule is integrity-tested to meet the highest quality standards and safety regulations. Consumables Water purification on a laboratory scale 7 – Horizontal installation, optimized temperature gradient – Effective breakdown of organic compounds – Prevents the growth of microorganisms – Easy replacement arium® UV Lamp (185|254 nm) Ultrapure water, free of TOC Description The horizontally arranged UV lamp delivers especially reliable results. Unlike vertical units, the temperature gradient is less pronounced and does not affect the activity of UV radiation. The two different wavelengths reliably remove organic substances (TOC), effectively preventing microbiological growth. At 185 nm organic compounds are oxidized, and at 254 nm microorganisms are killed. Material Fused silica TOC value for product water* < 5 ppb Order Number Description H2O-CEL1 arium® UV lamp (185|254 nm), (1 pc) Intended Use arium® mini and arium® mini plus Technical Specifications | Ordering Information * Depending on feed water and used system type arium® mini plus Pre-treatment Cartridge Reliable protection for the treatment of feed water Technical Specifications | Ordering Information Description Efficient purification via a combination of activated carbon, a catalyst and a downstream reverse osmosis membrane. The spherical, catalytic-effective, activated carbon and an additional catalyst reliably remove oxidation agents such as free chlorine and ozone, heavy metal ions and particulate contaminants from the feed water. In addition, due to the downstream reverse osmosis membrane, up to 98% of all salts, as well as bacteria and particles are removed. Materials Housing High-quality polypropylene Filtration media Spherical, catalytic activated carbon Dimensions [W×H×D] 18×26×11 cm Operating weight 3.5 kg Feed water requirements See “Technical Specifications” page 3 Order Number Description H2O-CPR arium® mini plus Pre-treatment Cartridge (1 pc) Intended Use arium® mini plus – Fast and effective adsorption of impurities through high-grade activated carbon – Highly efficient catalyst for removing oxidation agents such as chlorine – Highly efficient reverse osmosis membranes, optimized water consumption – Low-energy membranes for ecological and economical operation Water purification on a laboratory scale 9 – Easy and fast replacement of the arium® Bag – High user safety due to the avoidance of cleaning chemicals arium® Bag The most innovative tank system Technical Specifications | Ordering Information Description The pure water is stored in the device. This system protects the prepared pure water against secondary contamination. The Sartorius bagtank technology enables consistent water quality over a prolonged period, thereby ensuring permanent, reproducible results. Unlike conventional water reservoirs, the arium® Bag offers a high level of user safety and time savings, as there is no need for a complicated cleaning procedure with chemicals. Materials Bag S71, 6-Layer high gas barrier film Tubing TuFlux® Bag dimensions [H × W] Bag 5 liters 40 × 33 cm Order Number Description H2O-CBS-5-S arium® 5 liter Bag (1 pc) Intended Use arium® mini and arium® mini plus – High performance capacity thanks to efficient ion exchange resins – Fast and effective adsorption of impurities through high-grade activated carbon arium® Scientific Pack Deionization cartridge featuring top-down-flow technology Description The cartridge sets are optimized for the removal of both organic and inorganic constituents. The set was designed specifically to match the unit and delivers ultrapure water that exceeds the ASTM Type 1 quality standard. This consistent level of high-quality water ensures optimal reproducibility of your results. Optimized filling materials, such as highly effective activated carbon coupled with highly efficient ion exchange resins, deliver long lasting performance and low-maintenance operation. The top-down flow technology produces ideal purification kinetics and prevents any mixing of cleaning media. The cartridge was designed with the flow rate in the cross section and contact time with the medium in mind. Materials Housing High-purity polypropylene Filtration media Spherical, catalytic activated carbon Ultrapure mixed bed ion exchange resin in semiconductor quality Further data on product water quality See “Technical Specifications” page 3 Order Number Description H2O-S-PACK arium® Scientific Kit (1 pc) Intended Use arium® mini and arium® mini plus